Whole blood filtration.

Whole blood filtration.

Filtration Parameters Influencing Circulating Tumor Cell Enrichment from Whole Blood

Filtration can achieve circulating tumor cell (CTC) enrichment from blood. Key parameters such as flow-rate, applied pressure, and fixation, vary largely between assays and their influence is not well understood. Here, we used a filtration system, to monitor these parameters and determine their relationships. Whole blood, or its components, with and without spiked tumor cells were filtered thro...

Separation of whole blood into plasma and red cells by using a hollow-fibre filtration system.

BACKGROUND AND OBJECTIVES The aim of this study was to assess the separation of whole blood into red cells and plasma by using the Sangofer device, which is a gravity-fed, hollow-fibre system. The components would then be compared with those produced by the use of more elaborate technical equipment. MATERIALS AND METHODS Ten whole-blood units were leucoreduced by using a WBF2 filter and immed...

Plasma quality after whole-blood filtration depends on storage temperature and filter type.

The study evaluated the quality of plasma obtained after whole-blood filtration with four different polyester filters and one polyurethane filter. The activities of coagulation factors and proteinase inhibitors were not or only negligibly affected by filtration, in all experiments. Filtration did not increase markers of clotting and fibrinolysis. Only a strong neutrophil and complement activati...

Blood Filtration During Cardiopulmonary Bypass

Particulate microembolization during extracorporeal circulation is thought to contribute to cerebral, pulmonary and other post-operative complications following cardiac surgical procedures. 11° Factors which have been implicated in microembolic phenomena during cardiopulmonary bypass include: 1 ) transfusion of stored blood ,I· 2 ' '· 11 ' ' 3 22 2) formation of platelet aggregates in the patie...